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Dipeptidyl Peptidase-4 Inhibitors versus Other Antidiabetic Drugs Added to Metformin Monotherapy in Diabetic Retinopathy Progression: a Real World-Based Cohort Study

Additionally, tirzepatide acts on appetite regulation centers in the brain, promoting satiety and reducing caloric intake, which contributes to weight loss

Reduces orange peel-like fatty tissues

When a Bonferroni correction was applied, levels of 4 metabolites (-GluCys, LA, D-lactate, and Trp) were still significantly different between control and patient groups, while the following metabolites were present at similar levels in both groups: AA, Kyn, D-Ser, Glu, 3-HB, GSH, 5-HT, Thr, and Tyr (Table 2)

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